Tuberculosis in Young Adults
نویسنده
چکیده
ADULTS; Report on the Prophit Tuberculosis Survey, 1935-44, Royal College of Physicians. London: H. K. Lewis. 1948. 30s. THIS extensive report (227 pages, 58 X-ray plates, 99 statistical tables, and 22 charts) contains an account of the most comprehensive survey so far carried out in England. Following the earlier work in Scandinavia and North America, the planning of the work has obviously benefited by the earlier experience of foreign epidemiologists. The material is composed of five groups of the population: (1) Contacts, who were mainly family contacts of tuberculous patients; (2) Controls drawn from the general population, and excluding tuberculous patients; (3) Nurses working in London hospitals; (4) Medical students; (5) Boys in naval training schools. The technique of the survey inicluded Mantoux testing, chest radiology, and other clinical investigations as necessary at annual intervals. Approximately 10,000 persons were studied, although the original plan of the survey had to be curtailed owing to the war. The mass of observations accumulated by the Prophit scholars has been set out with great clarity and in full detail, and thus forms a most valuable factual record regarding tuberculosis in England. One of the most interesting findings is the excess of tuberculosis morbidity and mortality among the Irish and Welsh nurses working in London. After full consideration of thle Xvarious factors which may contribute to this definitely increased liability to tuberculosis, it appears clear that the genetic factor has at least some influence. Although the report is mainly of interest to epidemiologists and tuberculosis workers, it forms also a valuable clinical record. The finding that forty-one cases considered inactive when first examined broke down subsequently, is an important pointer to the need for prolonged observation of the doubtfully active, "early" tuberculous adult. The conclusions of the Prophit scholars are well worthy of serious consideration, as they are based on carefully observed facts xwhich have been closely scrutinised and fully discussed by a committee whose names must inspire respect. The report shows a definite bias irt favour of th exogenous theory of superinfection, and those who wish to read both sides of the question should refer to A. L. Jacob's critical review in Tubercle, September, 1948. The Prophit Survey is one of the most valuable publications regarding tuberculosis which have appeared in Great Britain of recent years. B. R. L.
منابع مشابه
Status of Exudative Pleural Effusion in Adults of South Khorasan Province, Northeast Iran: Pleural Tuberculosis Tending toward Elderly
The causes and situation of exudative pleural effusion vary from one area to another. A cross-sectional study was conducted on 327 patients with exudative pleural effusion in South Khorasan province (Iran). The patients were older than 12 years and comprised 172 (52.6%) males and 155 (47.4%) females. The study commenced in 2007 with seven years duration. The Light’s criteria were used to define...
متن کاملWhole Blood Interferon-Gamma Responses to Mycobacterium tuberculosis Antigens in Young Household Contacts of Persons with Tuberculosis in Uganda
BACKGROUND Due to immunologic immaturity, IFN-gamma-producing T cell responses may be decreased in young children compared to adults, thus we hypothesized that IFN-gamma responses to mycobacterial antigens in household contacts exposed to Mycobacterium tuberculosis (Mtb) would be impaired in young children relative to adults. The objective of this study was to compare whole blood IFN-gamma prod...
متن کاملRacial Differences in Tuberculosis Infection in United States Communities: The Coronary Artery Risk Development in Young Adults Study
Previously reported associations between race/ethnicity and tuberculosis infection have lacked sufficient adjustment for socioeconomic factors. We analyzed race/ethnicity and self-reported tuberculosis infection data from the Coronary Artery Risk Development in Young Adults (CARDIA) study, a well-characterized cohort of 5115 black and white participants, and found that after adjusting for socio...
متن کاملTuberculosis in young adults and the elderly. A prospective comparison study.
OBJECTIVES To compare the clinical, bacteriologic, and radiologic features of pulmonary and pleural tuberculosis in young adults and the elderly and determine if any differences exist between both groups. DESIGN Prospective recruitment of all patients diagnosed as having pulmonary and pleural tuberculosis in British Columbia, Canada. SETTING A population-based sample from a provincial contr...
متن کاملدرمان کوتاه مدت بیماری سل با نظارت مستقیم (روش درمانی DOTS)
The resurgence of tuberculosis in recent years has made an effective control strategy in indispensable. The strategy exists and is called Directly Observed Treatment, Short-course (DOTS) which is the worldwide best and Practical approach. In a five year period since the (DOTS) was adopted by WHO as a strategy to combat tuberculosis worldwide, more than 1.2 million people have received this tre...
متن کاملA Young Lady with a Swelling over the Back: A Rare Case of Tuberculosis
Musculoskeletal tuberculosis accounts for 1-2% of all types of tuberculosis. Tubercular abscess of the chest wall accounts for 1-5% of all cases of musculoskeletal tuberculosis. Herein, we report a case of tubercular abscess of the chest wall. The occurrence of caries rib and cold abscess of the chest wall with concomitant pulmonary tuberculosis, and tubercular lympha-denitis of neck and medias...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- The Ulster Medical Journal
دوره 18 شماره
صفحات -
تاریخ انتشار 1949